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TB and HIV Diagnostic Assay
Dr. Kabamba Alexandre
Angola
Through the CSIR Bioscience Unit Array Printing Technology Platform the pilot study for this innovation aimed to address drug discovery limitations by developing a point of care multiplex microarray technology for simultaneous detection of HIV and M.tb in blood. This solution aimed to reduce time and costs associated with the diagnosis of these diseases. The microarray-based diagnostic technology involves the detection of antibodies against HIV p24 antigen, as well as antibodies against M.tb antigens ESAT6, CFP10, apa and pstS1 that together are markers of active TB. This technology will be complemented by the development of a portable, battery powered and low-cost fluorescence reader medical device for detecting antibodies against these antigens at the point of care.